New insights in cell biology. Layouts summarize new insights, such as epigenetic changes, mitochondrial biogenesis and post-translational protein modifications responsible for cell cycle regulation. There are several medical issues where basic cellular procedures failure.
The lecture is focused on the destiny of sperm mitochondria after oocyte fertilization and the mechanism of mitophagy of sperm mitochondria. Sperm mitophagy-derived diseases are mentioned and the genesis during early embryonic development is explained.
The lecture brings the outlines of gametogenesis (progenesis), the process of fertilization and pre-implantation early embryonic development. Notes to embryo implantation and the embryo-endometrium crosstalk are included.