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Author: Jan Nevoral, prof. MUDr. Králíčková Milena, Ph.D.
The lecture brings the outlines of gametogenesis (progenesis), the process of fertilization and pre-implantation early embryonic development. Notes to embryo implantation and the embryo-endometrium crosstalk are included.
Author: Jan Nevoral, Lukáš Gold
New insights in cell biology. Layouts summarize new insights, such as epigenetic changes, mitochondrial biogenesis and post-translational protein modifications responsible for cell cycle regulation. There are several medical issues where basic cellular procedures failure.
Author: Vladimír Rogalewicz
In modern medicine, evaluation of experiments based on evidence (evidence-based medicine) is strictly required. If statistical methods are correctly applied and their results correctly interpreted, then the utilization of modern methods of mathematical statistics significantly reduces the danger of an incorrect interpretation of the experiment.
Author: Jan Nevoral, Peter Sutovsky, Won-Hee Song
The lecture is focused on the destiny of sperm mitochondria after oocyte fertilization and the mechanism of mitophagy of sperm mitochondria. Sperm mitophagy-derived diseases are mentioned and the genesis during early embryonic development is explained.
Author: Kari Hemminki
Prof. Hemminki is a leading specialist of the field of epidemiology and genetics of many types of cancer. It comes from Finland and began studying medicine at the University of Helsinki. In his lecture he summarized the current state of knowledge and future directions of research in tumor biology.
Author: Václav Zeman
Doping is a great problem of contemporary sport. The article describes doping substances and methods. Harmful effects of doping are also listed. This article is suitable for 4th year students of general medicine.
Lecture from Sports medicine for medical students 4th year. The basic concepts were presented. Maximal oxygen uptake, stress (lactate) threshold and lactate curve were elucidated. ST fibers, FTa and FTb fibers were presented.
Author: Alain G. Zeimet
Decades of research and bilions of dollars in funding have revealed much about the molecular events that lead to center. But overall, today's cancer cure rates are not much better than they were 30 years ago. Decades of research and bilions of dollars in funding have revealed much about the molecular events that lead to center.
The lecture for students of generally medicine 4th year – The field: sports medicine. Principles of performance (exercise, stress) testing are introduced. Oxygen consumption (incl. VO2 max) and lactate curve are elucidated. Indication and contraindication of exercise tests are introduced. Both ECG and symptomatic indicators of coronary heart disease are discussed.
Author: Milan Hora
mainly mycotic - diabetics –combination with diabetic phimosis –healthy men –intercourse with woman with mycotic vaginitis –Treatment, local antimycotics (Clotrimazolum), in phimosis -circumcision
Non -malignant enlargement of prostate. Etiology unknown, a lot of theories may be related to an imbalance between estrogenic and androgenic activity. Histopathology. BPH – histhological diagnosis, patient comes because of voiding problems – LUTS (lower urinary tract symptoms).
Bladder and urethra –a functional unit for storage and periodic expulsion of urine (micturition), storage and micturition are coordinated by different parts of CNS –functional disorders at every level cause neuropathic bladder, neuropathic bladder is a term apllied to voiding problems due to neurologic dysfunction of urinary bladder
Author: Milan Štengl, Jitka Švíglerová, Tomáš Ťupa, Ivana Hajdúková
The spontaneous production of impulses in the heart is demonstrated with help of the Langendorff apparatus. In isolated, retrogradely perfused heart the spontaneous rhythmical activity is maintained.The spontaneous production of impulses in the heart is demonstrated with help of the Langendorff apparatus. In isolated
2nd most frequentinfectionatall(1st –RTI), mostlyascending, normalurinarytractissterileupto distalurethra
predisposingfactors, pathogenes–Gram negative bacteria–in 90 %,...
incidence C60 in CZ 2004 1,1/ 100 000 men/y, rarein circumcisedatbirth(Jewsandotherreligiousgroups), Precancerosis, Carcinomain situ
1. Urinary tract infections, urolithiasis
2. Lower urinary tract dysfunctions (BPH - benign prostatic hyperplasia, neuropathic urinary bladder, urinary incontinence)
3. Urooncology – tumors of kidney, urinary bladder, prostate and testicle
4. Benign diseases of male genitalia, the most important urogenital anomalies, andrology
5. Operative approaches in urology, urological emergency
used to be a branch of General Surgery, but several last decades a separate specialization, extensive diagnostics and conservative treatment, broad range of operative methods, broad range of operative methods
Author: Milan Štengl, Tomáš Ťupa, Jitka Švíglerová, Ivana Hajdúková
Teaching video shows the negative chronotropic effect of vagus nerve in rat heart.
Author: Milan Hora, a kol.
Frequency - normal adult voids five or six times per day, with a volume approximately 300ml with each void, often voiding = polakisuria (lat.)
Nocturia - frequent passage of urine during the night (nocturnal frequency)
Urgency - an overwhelming desire to pass urine immediately
Urge incontinence - wetting when voiding cannot be instituted quickly enough
Dysuria - pain on voiding, that is usually caused by inflammation
Author: Miroslav Dvořák
Alcohol is one of the oldest and most widely used psychoactive drug in the world and most common single substance encountered in toxicologic analyses. Ethanol (ethyl alcohol) is the main psychoactive ingredient in alcoholic beverages. The clinical features of acute ethanol intoxication are dependent on the blood concentration (BAC). Acute alcohol poisoning is life-threatening condition that requires emergency medical attention.
For ethical reasons the presentation on Mefanet does not contain photographs.
Author: Milena Králíčková, Zbyněk Tonar, Jitka Kočová, Věra Křížková, Alena Němečková, Miroslava Čedíková, Lukáš Nedorost, Lada Eberlová, Pavel Pitule
This textbook is recommended for revision the students' knowledge before taking the final examination in Histology and Embryology. There are 835 exam questions for both General and Dental Medicine students covering cytology, general histology, special histology, and embryology. There is a key to the answers and a list of recommended textbooks attached.
Academic Year Summer 2010/2011
Author: Jitka Švíglerová, Jitka Kuncová, Tomáš Ťupa, Jaromír Holas, Ivana Hajdúková
Teaching video demonstrates determination of plasma volume by means of Evans blue dye and the effect of intravenous injection of hypertonic glucose solution on plasma volume in rat.
Author: Michal Krčma, Zdeněk Rušavý
Thyroid gland disorders - study material in English in a range of lectures in internal medicine for the general direction
The major topics in Legal/Forensic Medicine are Thanatology and Forensic Pathology, Clinical Forensic Medicine, Medical Law and related Jurisprudence. Forensic pathology applies the principles of pathology to the study of sudden, unexpected, violent, and suspicious death in order to determine the cause, mechanism and manner of death.
For ethical reasons the presentation on Mefanet does not contain photographs.
Author: Jitka Švíglerová, Petr Králíček
The teaching material consists of two thematic groups: Evoked cortical potentials and Electroencephalography (EEG). The part dedicated to EEG clarifies origin of EEG signal, registration methods, EEG rhythms and EEG use.
Author: Lukáš Nalos, Jitka Švíglerová
This teaching material consists of a text part (see below) and an animation. The text part contains the detailed description of the individual phases of the cardiac cycle. The animation shows the mechanical events in the heart during the cardiac cycle including the arterial pulse, electrocardiogram, heart sounds, venous pulse, pressure and volume changes in the right atrium and in the left ventricle.